Identification of methylation pattern in the partial promoter of acetyl CoA carboxylase beta (ACACB) gene in White Leghorn line

The present study was initiated with an objective of identifying methylation pattern in the partial promoter Acetyl CoA carboxylase beta (ACACB) gene White Leghorn IWK line. To understand epigenetic regulation expression, birds highest and lowest expression at 18th week 40th age were chosen. Epigenetic profile minimal indicated that there seven CpG islands this region, positioned 75, 87, 155, 269, 284, 311 426 positions 555 bp region. Among these, except position remaining showed cis-acting transcription factors. There negative relationship between expressed per cent mean found to be 42.85 21.42 weeks age, respectively. results decrease age. overall 32.14 observed.